Pectus Excavatum bibliography

Bibliography

The best of scientific publications about treatment for Pectus Excavatum and Poland Syndrome with 3D custom-made implants.

Articles on the complications arising from the use of orthopaedic techniques (Nuss or Ravitch) in the treatment of Pectus Excavatum.

As well, a selection of articles about custom-made 3D tracheobronchial stents

Plastic and Reconstructive Surgery Journal article on Poland Syndrome

PRS - Correcting Poland Syndrome with a Custom-Made Silicone Implant

Plast Reconstr Surg. 2018 August;142(2) - Chavoin J.P., Taizou M., Moreno B., Leyx P., Grolleau J.L. , Chaput B. This article is based on 25 years of experience and 129 patients with Poland Syndrome treated by 3D custom-made implant. It demonstrates that this technique can achieve high quality aesthetic results (more than 90% of the aesthetic results are considered excellent) and thus respond to the psychological impact of this pathology.

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PRS Journal Pectus Excavatum

PRS - Correction of Pectus Excavatum by Custom-Made Silicone Implants: Contribution of CAO

Plast Reconstr Surg. 2016 May;137(5) - Chavoin J.P., Grolleau J.L. , Moreno B., Dahan M., Chaput B. This article is an overview of the experience of 401 cases. It also shows how this technique is the best response to patients' demands (80% of patients were satisfied or very satisfied). The technique is simple and reliable in addition to offering high-quality results. In the short term, this procedure may result render other orthopaedic techniques obsolete, such as the Nuss or Ravitch techniques, which are much more invasive.

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2019 Springer Publication about Pectus Excavatum and Poland Syndrome

Springer - Pectus Excavatum and Poland Syndrome Surgery

Chavoin J.P., Editor © Springer Nature Switzerland AG 2019. It makes original focus as the impact of Pectus and Poland on breasts or the potential respiratory or cardiac disorders associated to the pathology. It also presents alternative surgeries such as remodelling techniques (Nuss or Ravitch), with the risks associated to these last ones. This book demonstrates that in a majority of indications, the technique of custom made implants is the most suitable, providing high quality aesthetic results, while minimizing risks for…

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BMJ Journals publication: Double bifurcated airway stent

‘Double-bifurcated’ stent: when 3D is not an option

N Guibert, J Mazières, B Moreno, H Dutau, G Plat, V Héluain, R Kessler, M Porzio - BMJ Journals thorax-2022-219954 - After a tracheal and carinal resection in 2016, the patient developped stenoses of the trachea and bronchus (dyspnoea). Since 2019, 15 stents had to be removed for severe adverse events. Then he was enrolled in the TATUM trial to get a 3D custom-made silicone implant stent. This stent has now been in place for 7 months and the patient reported some dramatic improvements in dypnoea and quality of…

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European Journal of Cardio Thoracic cover picture

Pulmonary function following surgical repair of pectus excavatum

Malek MH, Berger DE, Marelich WD, Coburn JW, Beck TW, Housh TJ. - Eur J Cardiothorac Surg. 2006 Oct; 30(4):637–43. - This article examines the effectiveness of the surgical repair of Pectus Excavatum on lung function. Twelve studies have been conducted to address cases of 313 patients with Pectus Excavatum. The results indicate that the surgical repair of Pectus Excavatum does not significantly improve lung function.

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Pediatric Pulmonology Publication on Ventilatory Limitations on Pectus Excavatum

Pectus Excavatum and ventilatory limitations

William Hardie & al. - Ventilatory limitations are not associated with dyspnea on exertion or reduced aerobic fitness in Pectus Excavatum - Pediatric Pulmonology 18 June 2021 - Exercice intolerance and chest pain are commun symptoms in PE but in this 259 patients’ study, a pulmonary limitation during exercice was identified in less than 3% of them. Limitations on pulmonary function tests was classified mild in 85% and have poor correlation with the anatomic extent of pectus defect.

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Aesthetic Surgery Journal publication on calf atrophy

ASJ - Correcting of Calf Atrophy With a Custom-Made Silicone Implant

Contribution of Three-Dimensional Computer-Aided Design Reconstruction: A Pilot Study - Aesthetic Surgery Journal, 27 June 2020 - Jean-Pierre Chavoin, Elise Lupon, Benjamin Moreno, Pierre Leyx, Jean-Louis Grolleau, Benoit Chaput - Our innovative procedure to correct calf atrophy with custom solid rubber silicone implants produces a calf shape that better adapts to volume loss than prefilled silicone gel implants

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Journal Plos One

Trace metal release after minimally-invasive repair of pectus excavatum

Fortmann C., Göen T., Krüger M., Ure B. M., Petersen C., Kübler J. F. - October 12, 2017, Hyun-Sung Lee, Baylor College of Medicine, USA - Comparative study on 20 young patients with unoperated pectus excavatum and 20 others treated by Nuss technique. When metal bars were removed after 3 years, she noticed an abnormally high level of nickel and chromium in blood and urine. Three years after the bars removal, she still finds high levels of these same metal particles.

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Cirugía Española

Experience with the Nuss technique for the treatment of pectus excavatum

Cir Esp 2016 Jan;94(1):38-43 - Fibla J.J., Molins L., Moradiellos J., Rodríguez P., Heras F., Canalis E., et al. - Although the Nuss technique revolutionised the surgical treatment of pectus excavatum, its use has not become widespread in Spain. The aim of this study was to analyse the use of this technique between 2001 and 2010 in a sample of Thoracic Surgery Departments in Spain. The risk of complications must be taken into account and its indication must be properly evaluated. 30.6% out of the 149 patients participating in…

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Journal of Cardiothoracic and Vascular Anesthesia

Perioperative anesthetic and surgical complications of the Nuss procedure

J Cardiothorac Vasc Anesth. 2013 Jun; 27(3):436–40 - Umuroglu T, Bostancı K, Thomas DT, Yuksel M, Gogus FY. - The Nuss procedure consists of reconstruction surgery on the chest wall on patients with Pectus Excavatum. Although the Nuss procedure is considered only somewhat invasive, attention must be paid to some of the serious complications associated with surgery and anaesthesia. The complication rate out of the 240 patients studied was 18.7%. Intraoperative hypotension, tachycardia, and hypercapnia are the most common…

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Secondary surgeries

The pectus excavatum: Secondary surgery with implants

Annales de Chirurgie Plastique Esthétique - Volume 64, Issues 5–6, Nov 2019, Pages 620-633 - J.-P. Chavoin, J.-L. Grolleau, B. Chaput, B. Moreno, F. Le Pimpec Barthes, J. Assouad, L. Brouchet, M. Dahan - Pectus Excavatum is the most common malformation of the thorax. Several surgical or medical techniques have been proposed. Some are followed by complications or insufficient results. Secondary surgery with a deep customized 3D implant, may be an elegant and effective solution.

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BMJ Journals Thorax new publication

Treatment of complex airway stenosis using patient-specific 3D-engineered stents

Nicolas Guibert et al. - Treatment of complex airway stenoses using patient-specific 3D-engineered stents: a proof-of-concept study - BMJ Journals Thorax, Volume 74, issue 8 - Anatomically complex airway stenosis (ACAS) represents a challenging situation in which commercially available stents often result in migration or granulation tissue reaction due to poor congruence. A clinical trial of 3D stents has been carried out as a solution for this issue.

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Pediatric Surgery journal cover

Catastrophic Cardiac Injuries during Repair of Pectus Excavatum

Bouchard S, Hong AR, Gilchrist BF, Kuenzler KA. - Semin Pediatr Surg. 2009 May;18(2):66-72. - This paper presents four severe cardiac injuries that occurred in patients who underwent the minimally invasive repair of pectus excavatum (MIRPE). These complications occurred in different clinical settings, namely in a patient with an extremely severe form of pectus, in a patient who had previously undergone an open repair, after a previous open heart surgery, and at the time of bar removal.

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Article of Respiratory Medicine : 3D printing

Integration of 3D printing in pulmonologist's toolbox

Respiratory Medicine, Volume 134, January 2018, Pages 139-142 - Nicolas Guibert, Laurent Mhanna, Alain Didier, Benjamin Moreno, Pierre Leyx, Gavin Plat, Julien Mazieres, Christophe Hermant - New 3D technologies are rapidly entering into the surgical landscape, including in interventional pulmonology. This article focus on the clinical experience in Toulouse which used 3D printing anatomical models of airways to prepare the most delicate interventions.

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ATS Journal article : Computer-assisted Customized Airway Stent

Computer-assisted Customized Airway Stent (Complex Airway Stenosis)

AJRCCM, Vol. 195, No.7 I Apr 01, 2017 - Guibert N., Didier A., Moreno B., Mhanna L., Brouchet L., Plat G., Hermant C., Mazieres J. - The complex anatomy of some patients with airway pathology excludes the use of conventional stents. A custom-made 3D stent was successfully developed and implanted at the Toulouse University Hospital in a pulmonary transplant patient. The article explains the results, with perfect congruence and immediate improvement of the quality of life of the patient.

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